Middle Eastern Health Click to Read Full Article in PDFStatins and Cancer - The Hidden Story
Brian S. Peskin, with David Sim, MD and Amid Habib, MDAs early as the late 1990s, almost half of all Americans and Europeans died of heart disease. By 2010, virtually all Americans are predicted to die either of heart disease or cancer. Atherosclerotic coronary artery disease (CAD), a “clogging” of the arteries, became the number one killer of Americans in 2006, with cancer a close second. Now, in spite of widespread use of cholesterol-lowering drugs, heart disease remains the top killer in Western countries as well as in the Middle East.
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Medical Hypotheses Click to Read Full Article in PDF
Chronic cellular hypoxia as the prime cause of cancer: What is the de-oxygenating role of adulterated and improper ratios of polyunsaturated fatty acids when incorporated into cell membranes?
Brian S. Peskin a,*, Marissa J. Carter ba. Swing Aerobics Licensing, Inc., P.O. Box 56507, Houston, TX 77256, United States
b. Strategic Solutions, Inc., Cody, WY 82414, United States
Received 14 May 2007; accepted 22 May 2007Summary: With the exception of melanoma and non-Hodgkin’s lymphoma, the incidence of cancer has peaked in the last several years, but rates and mortality are still high. Moreover, despite 50 years of intensive cancer research increasingly focused on genetic causes, no single unifying cause for cancer has been established. Although it is well- known that tumors are hypoxic, and that there is a correlation between the level of hypoxia and prognosis, with the exception of Warburg’s studies, little work has been done to investigate the relationship between hypoxia and cancer. Over 70 years ago, Warburg showed that cells could always be made cancerous by subjecting them to periods of hypoxia. Moreover, he demonstrated that once cells had converted to a cancerous state, reversion could not occur. Modern biochemistry acknowledges that there is a switch from oxidative phosphorylation to glycolysis in tumors that might be concurrent with hypoxia, but does not address the cancer causation. It is our hypothesis that long-term hypoxia of cells in the body, measured in years, is the primary trigger for cancer. We believe that the hypoxia, which has to meet Warburg’s €ndings of a critical 35% reduction in intracellular oxygen levels to initiate cancer, is linked to the incorporation of adulterated, non-oxygenating, or inappropriate polyunsaturated fatty acids (PUFAs) into the phospholipids of cell and mitochondrial membranes. Such incorporation causes changes in membrane properties that impair oxygen transmission into the cell. Trans fats, partially oxidized PUFA entities, and inappropriate omega-6:omega-3 ratios are all potential sources of unsaturated fatty acids that can disrupt the normal membrane structure. In this paper, we explore this hypothesis by examining the evidence, and additionally propose an appropriate PUFA dosage for humans by analyzing requirements and taking into account current PUFA consumption patterns.
© 2007 Elsevier Ltd. All rights reserved.Click to Read Full Article in PDF
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AHA revises statement on soy protein:
Benefits "minimal at best"
Jan 20, 2006 Shelley Wood
Dallas, TX - Five years after it released a scientific advisory recommending the inclusion of soy-protein foods in a diet low in saturated fat and cholesterol, the American Heart Association has issued a revised statement, going back on its earlier advice.
"The direct cardiovascular health benefit of soy protein or isoflavone supplements is minimal at best," the new advisory states. "[U]se of isoflavone supplements in food or pills is not recommended."
The new statement was published January 17, 2006 this week as a rapid access paper in Circulation online [1].
For their analysis, the writing committee, led by Dr Frank M Sacks (Harvard School of Public Health, Boston, MA), examined 22 randomized trials comparing the effects of isolated soy protein with isoflavones with milk or other proteins. They report that while soy products seemed to reduce LDL cholesterol, the effect was trivial (around 3%) and only in people who ate a lot of soy protein—roughly half their daily protein intake. No effects of soy protein were seen on HDL, triglycerides, lipoprotein (a), or blood pressure. In 19 of 22 studies, the effect on all lipid parameters was nil.
The recommendation for physicians, Sacks told heartwire, is to tell their patients "not to use isoflavone supplements, since they are ineffective. Soy protein is not much better than other proteins for cardiovascular health. A large amount lowers LDL a little bit and does not affect the other CV lipids and other risk factors."
Soy effects for other diseases: Mixed or nil
The statement authors also point out that studies examining soy's effects on postmenopausal bone loss have been mixed and have failed to show a clear benefit of soy for vasomotor symptoms of menopause (hot flashes) or prevention of breast, endometrium, and prostate cancer. People should look at the nutrient content of anything they buy.
Of note, the statement distinguishes between isoflavone supplements and soy-based foods, since foods that are high in soy may have some cardiovascular benefits. Unlike animal-based proteins, soy-based foods such as tofu, soy butter, soy nuts, and some soy burgers typically contain polyunsaturated fats, fiber, vitamins, and minerals, but low amounts of saturated fat, the authors note. In some settings, they say, replacing proteins high in saturated fats with soy-based protein might translate into cardiovascular benefits.
Life-Systems Engineering Science Note: Saturated fat is NOT dangerous or in any way unhealthy because there is no saturated fat in arterial clogs and this was analyzed and published in Lancet back in 1994! Read Professor Peskin's landmark book The Hidden Story of Cancer for the full story of LDL Cholesterol! ALL Natural fats, whether they be cheese, cream, butter or the fat on meat, are healthy and needed for good health. The dangerous fats are transfats and artificial fats.
But as with other fad foods of the past decade, it's important to read the labels, Sacks points out. "People should look at the nutrient content of anything they buy. Some of the soy products are quite good but others may not be. . . . If the soy protein is in a product that has low salt, no trans fat, and low saturated fat and has other healthy ingredients like polyunsaturated fats and fiber that are in soybeans, then the food would be good for CV health," he said.
Life-Systems Engineering Science Note: Professor Peskin's more than decade long studies in health and science have shown, and proven that eating lots of vegetables and fiber are NOT healthy and don't provide nutrition or any benefit to protect you from disease. On the contrary, too much fiber can actually lead to the development of colon cancer! The Professor's landmark book The Hidden Story of Cancer has the full story!
Source: Sacks FM, Lichtenstein A, Van Horn L, et al. Soy protein, isoflavones, and cardiovascular health. A statement for professionals from the American Heart Association nutrition committee. Circulation 2006; DOI: 10.1161/. Available at: http://www.circulationaha.org.